Uncertain Inheritance: Transgenerational Effects of Environmental Exposures

Uncertain Inheritance: Transgenerational Effects of Environmental Exposures

Transgenerational Effects of Environmental Exposures

Transgenerational Effects of Environmental Exposures

Environmental stress and epigenetic transgenerational inheritance

Previous studies have shown a wide variety of environmental toxicants and abnormal nutrition can promote the epigenetic transgenerational inheritance of disease. More recently a number of studies have indicated environmental stress can also promote epigenetic alterations that are transmitted to subsequent generations to induce pathologies. A recent study by Yao and colleagues demonstrated gesta...

Environmental epigenetic transgenerational inheritance and somatic epigenetic mitotic stability.

The majority of environmental factors can not modify DNA sequence, but can influence the epigenome. The mitotic stability of the epigenome and ability of environmental epigenetics to influence phenotypic variation and disease, suggests environmental epigenetics will have a critical role in disease etiology and biological areas such as evolutionary biology. The current review presents the molecu...